USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: O15145 USC-OGP 2-DE database:  O15145 O15145 General information about the entry View entry in simple text format Entry name ARPC3_HUMAN Primary accession number O15145 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Actin-related protein 2/3 complex subunit 3; AltName: Full=Arp2/3 complex 21 kDa subunit; Short=p21-ARC;. Gene name Name=ARPC3 Synonyms=ARC21 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-1066: pI=8.60; Mw=17639 Cross-references UniProtKB/Swiss-Prot O15145; ARPC3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ARPC3_HUMAN Primary accession number O15145 Secondary accession number(s) O00554 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 148) Name and origin of the protein Description RecName: Full=Actin-related protein 2/3 complex subunit 3; AltName: Full=Arp2/3 complex 21 kDa subunit; Short=p21-ARC; Gene name Name=ARPC3 Synonyms=ARC21 Encoded on Name=ARPC3; Synonyms=ARC21 Keywords Acetylation; Actin-binding; Cell projection; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF004561; AAB61466.1; -; mRNA EMBL AF006086; AAB64191.1; -; mRNA EMBL CR407667; CAG28595.1; -; mRNA EMBL BC067747; AAH67747.1; -; mRNA EMBL BC078162; AAH78162.1; -; mRNA CCDS CCDS9146.1; -; . RefSeq NP_001265485.1; NM_001278556.1; . RefSeq NP_001274151.1; NM_001287222.1; . UniGene Hs.524741; -; . ProteinModelPortal O15145; -; . SMR O15145; -; . BioGrid 115401; 81; . DIP DIP-33187N; -; . IntAct O15145; 61; . MINT MINT-156243; -; . STRING 9606.ENSP00000228825; -; . DrugBank DB08235; N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide; . iPTMnet O15145; -; . PhosphoSitePlus O15145; -; . SwissPalm O15145; -; . OGP O15145; -; . EPD O15145; -; . MaxQB O15145; -; . PaxDb O15145; -; . PeptideAtlas O15145; -; . PRIDE O15145; -; . TopDownProteomics O15145; -; . DNASU 10094; -; . Ensembl ENST00000228825; ENSP00000228825; ENSG00000111229; . GeneID 10094; -; . KEGG hsa:10094; -; . UCSC uc001tqq.5; human; . CTD 10094; -; . DisGeNET 10094; -; . GeneCards ARPC3; -; . HGNC HGNC:706; ARPC3; . HPA HPA006550; -; . MIM 604225; gene; . neXtProt NX_O15145; -; . OpenTargets ENSG00000111229; -; . PharmGKB PA25000; -; . eggNOG KOG3155; Eukaryota; . eggNOG ENOG4111FTG; LUCA; . GeneTree ENSGT00390000018018; -; . HOGENOM HOG000161465; -; . HOVERGEN HBG050581; -; . InParanoid O15145; -; . KO K05756; -; . OMA PLNAMYA; -; . OrthoDB EOG091G0OUM; -; . PhylomeDB O15145; -; . TreeFam TF314598; -; . Reactome R-HSA-2029482; Regulation of actin dynamics for phagocytic cup formation; . Reactome R-HSA-3928662; EPHB-mediated forward signaling; . Reactome R-HSA-5663213; RHO GTPases Activate WASPs and WAVEs; . Reactome R-HSA-8856828; Clathrin-mediated endocytosis; . SIGNOR O15145; -; . ChiTaRS ARPC3; human; . GeneWiki ARPC3; -; . GenomeRNAi 10094; -; . PRO PR:O15145; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000111229; -; . ExpressionAtlas O15145; baseline and differential; . Genevisible O15145; HS; . GO GO:0015629; C:actin cytoskeleton; TAS:ProtInc; . GO GO:0005885; C:Arp2/3 protein complex; IDA:FlyBase; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031941; C:filamentous actin; IEA:Ensembl; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0030426; C:growth cone; IEA:Ensembl; . GO GO:0030027; C:lamellipodium; IEA:Ensembl; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005200; F:structural constituent of cytoskeleton; IDA:FlyBase; . GO GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IDA:FlyBase; . GO GO:1990090; P:cellular response to nerve growth factor stimulus; IEA:Ensembl; . GO GO:0048013; P:ephrin receptor signaling pathway; TAS:Reactome; . GO GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome; . GO GO:0061024; P:membrane organization; TAS:Reactome; . GO GO:0006928; P:movement of cell or subcellular component; TAS:ProtInc; . Gene3D 1.10.1760.10; -; 1; . InterPro IPR007204; ARPC3; . PANTHER PTHR12391; PTHR12391; 1; . Pfam PF04062; P21-Arc; 1; . PIRSF PIRSF016315; ARP2/3_P21-Arc; 1; . SUPFAM SSF69060; SSF69060; 1; .

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